The sick, nauseating feeling in the pit of one's stomach after watching too many stupid, pointless videos possibly containing desperate yet failed attempts at humor, leaving the viewer begging for the answer to the question, "WHY??!!!!......"

CAUTION: YouTube Fever may result in one or more of the following: total loss of faith in humanity, desire to find the creator of certain videos and punch them in the face, feeling of hatred towards other humans in general, or, in rare cases, the loss of logical thought processing entirely.
Person 1: Dude, what's wrong with Joey?
Person 2: He just watched every "Fred" video created.
Person 1: Ouch... looks like he's got a bad case of YouTube Fever....
by jeaaaamangg June 30, 2009
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