A disease affecting the male of the species. Symptoms include single-mindedness, an obsession with sexual encounters, an inability to multitask, poor choice of response, lack of thoughtfulness of consequences, and inconsiderate behavior towards others. Most commonly misdiagnosed as "foot-in-mouth" disease.
A: "He said that my ass looked fat in the new jeans I bought!"

B: "Well, either he wasn't thinking, or he was incapable of reframing the sentence to blame it on the jeans instead of your ass. Either way, he's suffering from Y Chrome."
by Minionite July 29, 2014
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