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1) When one of your bros doesn't hang out with you in favor of his high maintenance or new girlfriend.

2)Being so ensnared to your girlfriend that you must always say yes to her and give in to her every beck and call because you don't want to make her so upset that you won't get laid anymore.
1) Bryan has been vagisolated ever since he got his new girlfriend; he has been "too busy" the last few times we called to hang out. I hope she doesn't have him by the balls!

2) Sorry I can't go with you guys down the shore; I am vagisolated this weekend; she needs me to assemble that desk she bought from IKEA and do some garden work around her house.
by Shho13 May 25, 2015
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