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1.-The name given to the new virus in resident evil 5, which was obtained from the progenitor virus and tends to turn live beings into some nasty bunch of leech-like stuff.
2.-A symbol of a snake devouring its own tail symbolizing the unity of all things.
1)-Damn! That uroboros wesker is some tough motherfucker, huh? -Yeah man, just shoot at it with rocket launchers till he snuffs it

2)-Do you think Nietzschgot the idea of Eternal Return from Uroboros? -No dude, he got that from the wheel of samsara
by heyandreiwhatsyournameagain March 21, 2009
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