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Tussed up is what happens when a large amount of robitussin cough syrup is consumed. You feel fine until you stand up and realize that you can no longer balance or talk normally.

Word invented by Douglas Coupland in his book "jPod."
I came home to find Jamie laying on the floor slurring her words. We had no alchol in the house. She must have been 'tussed up
by richardnixon July 14, 2008
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