Having a frustratingly itchy ass due to a mass amount of hair in the lower region.
Dude1: "Why do you keep squirming?"

Dude2: "My ass is on fire! It's abnormally hairy and its all entangled and tickling like crazy!"

Dude1: "The Sasquatch Effect is inevitable. Tough shit, I say."
by Pink Harmonica February 4, 2011
Get the The Sasquatch Effect mug.