Top definition
Not having an erection after watching "Shrek is Love, Shrek is Life" or really any media that includes Shrek.
Friend One: "So did you watch Shrek is Love, Shrek is Life?"
Friend Two: "Yeah that shit was disgusting"
Friend One: "C'mon bro, why you gotta have Shrektile Dysfunction on me"
by That One Pineapple December 14, 2014
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