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Shemosabe 

A very trusted and loyal female friend (to a guy or girl) ... in the spirit of Kimosabe, The Lone Ranger's faithful friend, Tonto.
Wake the fuck up, Shemosabe, and get your fucked up ass over here. You need to help me smoke up some of this killa loud I just got and let me tell you about the fucking ridiculous stupid shit that this crazy ass bitch I been fucking just said to me - I'm swear she makes your most extreme level of "crazy bitch" ( meant in the most affectionate way, and with all due respect, of course) seem like a valium vacation!
Shemosabe by Mr Serendipity July 28, 2017
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The Lone Ranger's very faithful companion, Tonto, called him "Chemosabe," often transcribed phonetically as kimosabe or kemosabe. Chemo- refers to drugs, while -sabe indicates knowledge.
I will do anything for chemosabe, in order to ensure he will continue to provide me with the drugs I need.
CHEMOSABE by Xeronimo December 4, 2018
A trusted friend and confidant who is also undergoing cancer-treatment.
Ranger Reid and Tonto probably remained in good health from both being outdoors in the fresh air and sunshine most of the time and apparently abstaining from any harmful substances like alcohol or tobacco, and so conceivably they would never have been in a position to call each other "chemosabe".
chemosabe by QuacksO July 11, 2023

Chemosabe, chemOsabe, AND chemosabE 

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