A condition where a charmingly personable young woman intimidates (and possibly scares off) the men she comes across due to her stunning grace, beauty, and assertiveness. This syndrome usually results in singleness and possible dabbling in lesbianism (as depicted in the movie "Frida").
STUNNINGLY ATTRACTIVE GIRL: I don't know what it is, but I seem to scare off any guy that I meet no matter how nice I am.
STUNNINGLY ATTRACTIVE GIRL'S BROTHER: That's because you have the Salma Hayek Syndrome, yo.
STUNNINGLY ATTRACTIVE GIRL'S BROTHER: That's because you have the Salma Hayek Syndrome, yo.
by jbvita February 13, 2007
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