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Stands for "Ripping my fucking dick off"
Used in cases when one, usually of male gender, is greatly upset with a situation.

In real-life conversation, the motion of pretending to grab the penis and forcefully removing it from the body is used, but only in extreme situations.
If you're at a party, and some asshole takes the last beer, an RMFDO moment is at hand.

"Dude, I took the rent money and blew it on some Chinese hookers."
"RMFDO"
by zeekee21 July 26, 2011
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