When you're obsessed with the idea of having sex with one woman that is not available to you (ex-girlfriends or women you wish to sleep with). It goes away after you manage to sleep with the said woman or after sleeping with another woman (generally a temporary cure).
A: Dude, why are you checking this chick's Myspace again?
B: I got the pussy curse for her, can't help it.

A: You spent all night talking to Jane, why don't you try hitting on someone else? You got the pussy curse?
by luizbf July 4, 2009
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