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1. Discrimination or prejudice based on a mole on one's skin.

2. A person with Moleism (a Moleist) has a prejudiced belief that having a mole makes a person inferior to those without.

3. Based on intolerance to a person with a mole/moles.
"As a Moleist, I believe in the ways of Moleism; particularly the belief that people who inhabit a fat mole/have fat moles (especially on their face) should live on a separate island called 'Mole Island'"
by Surina December 08, 2007
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