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Slang word in Spanish for any form of hit, crash, fall, or otherwise painful event where one object collides with another, car crash, punch in the face, falling down the stairs, etc.
2 cars crash violently "Que madrazo!"

Guy walks up with a black eye and fat lip "Que madrazo!"

Biker falls off motorcycle in mid air at 30 feet, bounces off the ground "Que madrazo!"
by El Antomadra February 03, 2010
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