Top definition
The act of being hogtied, gutted, and thrown from a window.

ORIGIN From the Latin roots Lubricus, Reus, Defenestra
Wow, did I actually see a real world application of lubrireus-defenestration? Crazy!

Alternatively:

Hannibal pulled some serious lubrireus-defenestration on inspector Pazzi's ass.
by Latinman! April 11, 2009
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