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1. Typically a term for professional fighting, but can be used in any fighting situation. Occurs when an individual literally "let's their hands go" and throws punches without thinking about any of them.

2. Going off pure punching instinct.

3. Puttin' a MF'er down.
It was a pretty close fight but you let your hands go and he was done in three seconds.
by RobTheReef November 17, 2009
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