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Alternative to the word "problem" with the same meaning.

My friends and I were at the pool one day and I overheard
them saying something, and it sounded as if one of them had a problem, and I don't know how it came out, but it did. I butt in and asked them "What's the isolem?" not knowing what I had just said, they all just busted out laughing, and then I realized what I had just said, it was just pretty bizarre and funny.

Now it's a common word among us, and we actually use it pretty often. It's great how things just happen randomly!
"Oh my god!"
"What's the isolem?!"

"Did you just..?"
"Do you have an isolem?"
Isolem by TomMac September 11, 2007
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A very rare person with a heart full of love and kindness and also sensitive to little things , likes to be dramatic sometimes
Islem is name of a person
islem by Eliza90 March 25, 2018

Methionylthreonylthreonylglutaminylarginyl...isoleucine 

The longest known word in English, at 189,819 letters, is the chemical name of titin. Titin is the largest known protein. This word takes roughly 3 hours to pronounce.
I can't use the full chemical name of titin because it goes over the word limit. So heres a shortened form:
I just learned today that Methionylthreonylthreonylglutaminylarginyl...isoleucine is the chemical name of the largest known protein to mankind.
Islem is a sweet guy who will always be there for you. Even when he’s upset with you he’ll always try to make you feel better. Islem is the guy everyone wants to be around. Though Islems can be very shy, theyre good at expressing their feelings. The guy every girl wants and the guy every guy wants to be around. He’s sweet. He’s attractive. He’s Islem
Person 1: Did you see that cutie that just walked by? He’s so sweet and humble.
Person 2: yeah he’s hot af! He’s sounds like an Islem 😍
Islem by alpucuh July 20, 2018

IStoleMadsLeg 

IStoleMadsLeg is a pretty famous roblox tiktoker! She loves her friends so much, that she’ll even make video’s about them. How cute is that?!? She has a small amount of friends, but they still help her with a lot of things! example: Maddie, Maya, Savannah, and Jax.
Player 1- OMG!! Is that IStoleMadsLeg?!
Player 2- OMGG!! I THINK IT IS!!
Player 1- LETS GO SAY HI!!
Player 2- YEA COME ON!! LETS GO!!
Player 1- THIS IS SO COOL!!
IStoleMadsLeg by Heyo!! February 1, 2021

METHIONYLTHREONYLTHREONYGLUTAMINYLARGINYL … ISOLEUCINE 

Note the ellipses. All told, the full chemical name for the human protein titin is 189,819 letters, and takes about three-and-a-half hours to pronounce. The problem with including chemical names is that there’s essentially no limit to how long they can be. For example, naming a single strand of DNA, with its millions and millions of repeating base pairs, could eventually tab out at well over 1 billion letters.
METHIONYLTHREONYLTHREONYGLUTAMINYLARGINYL … ISOLEUCINE Is a very long word

methionylthreonylthreonylglutaminylarginyl...isole 

A big ass word that mr. Beast read for over seventeen hours in a video.
Bab: Pneumonoultramicroscopicsilicovocanoconiosis is the biggest word
Beb: No, methionylthreonylthreonylglutaminylarginyl...isole is the biggest word!
Bab, Bib, Bob and Bub: IT'S ALMOST BEEN A FULL DAY, GO THE FUCK TO SLEEP