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1:A disease made up of four specific STDs/STIs. A combination of Herpes, Gonerhea, Sifilis, and last but not least, AIDS.

2:An insult to describe how dirty/slutty someone is.

pronunciation: herp-i-gon-a-sif-il-aids.
X: Dude, your girlfriend has been sleeping around.

Y: That's why I always use a condom.

X: Yeah man, for all we know, she could have Herpi-gona-sifil-aids.
by The Urban Dick January 19, 2011
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