A girl who is in her 20s but looks like she’s only 14 or 15.
All of the models at our agency all have Grande Syndrome. Hats the reason people like them.
by Justicewithtacosandweed August 14, 2018
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A relatively uncommon syndrome in which a brother and sister grow into two distinct people. The sister, or Ariana respectively, successfully climbs the ranks in society and is well praised for all aspects of themself, particularly looks. Meanwhile, the brother, or Franki, develops into a major flop that leads you to wonder where all the good-looking grande genes went.
Why can't William be as successful as Nicole?

Oh. I'm pretty sure he has Frankie Grande Syndrome.
by Simon THE CRAZY March 28, 2022
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