ESUE Share definition Flag An acronym that stands for Extra Skin Unless Erect. A name for somebody who is not circumcised. Pronounced eswee. Steven shared that he was uncircumcised yesterday. For that reason, we called him ESUE. ESUE by Elizabeth Beltem December 13, 2013 0 0 Get merch Get the ESUE mug. Buy Now — $32.95 See more merch