Bust a Hyme Share definition Flag To pop a cherry; to lose/take one's virginity.To break the hymen. "Yo have you and your girl done it yet?" "No but I'm gonna bust a hyme tonight." Bust a Hyme by yopeacenlove September 8, 2009 0 0 Get merch Get the Bust a Hyme mug. Buy Now — $32.95 See more merch