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Brain cell loss moment

Brain cell loss moment that can be several things including: Quite possibly the most annoying moment in your life where you become a dumbass for 5 seconds and after that you forget what you were trying to do (like walking into a room and forgetting why you walked in). Watching D.E.I training videos. Talking to a dumbass making yourself a dumbass (it can also work like a plague jumping person to person) until your intelligence kicks back in (which can be never). Trying to think of more definitions for this word. When you were about to watch a video but a short pops up and you watch and try to go back but it's gone.
Mike: *Walks into a room*
Mike: "Why the hell am I in here again?"
Mike: *thinks to himself* "Goddamn it I got Brain cell loss moment"
by HAMBURGER007 June 3, 2025
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Instant Loss 2koma

Refers to a 2-panel comic or sequence where a character initially expresses overconfidence only to get defeated and/or humiliated. The term originated in the manga fandom, and while it has SFW origins the term is now mainly used within hentai and yiff communities, where it is often used in a pornographic context.
Anonymous R34 Artist: "Wow I should post more instant loss 2koma. The one with Goku and Spongebob really popped off!"
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