wuddizzit Share definition Flag bay area slang for "what is it?", which can be used as a greeting in the same way as "wussup?" or "wuddup?". 1. wuddizzit my nigga??? 2. *phone rings* p1: hello? p2: WWWWUUUDDDDDIIIZZZIIIIITTT??!!! wuddizzit by monster of delight August 3, 2005 0 0 Get merch Get the wuddizzit mug. Buy Now — $32.95 See more merch