wacktose intolerant Share definition Flag Meaning you have no tolerance for wack shit; like lactose intolerant for milk, but "wack"tose intolerant. "Yo G, wanna hear my phat rhymes??" "Nah, man, I'm wacktose intolerant." wacktose intolerant by Crazy Irish Mike May 13, 2006 0 0 Get merch Get the wacktose intolerant mug. Buy Now — $32.95 See more merch