Predict-a-flu Share definition Flag A pathogenic virus that infects a person right around the time of a major event. "Sorry boss, looks like I can't come into work today, I got a case of the predict-a-flu on the day of the big game." Predict-a-flu by sage02 May 10, 2009 0 0 Get merch Get the Predict-a-flu mug. Buy Now — $32.95 See more merch