PUYB Share definition Flag An acronym short for Puff Up Your Boys. The phrase is often used by social groups to illustrate the desire to smoke marijuana without paying. I'm fiending some weed, can you please just PUYB tonight? I have no money PUYB by Puff Boy July 4, 2008 0 0 Get merch Get the PUYB mug. Buy Now — $32.95 See more merch
