Hiker's Curse Share definition Flag Hiker's Curse is a condition of burning in the butt region usually caused from inadequate wiping after a bowel movement. I've got a bad case of Hiker's Curse. Hiker's Curse by Click Spring December 14, 2017 0 0 Get merch Get the Hiker's Curse mug. Buy Now — $32.95 See more merch