Cossoff Share definition Flag The area between the scrotum and and ass hole. "Cossoff" it wasn't there, your insides would fall out. See also, Taint Just took an enourmous dump and took a splash back to the cossoff Cossoff by slaker November 8, 2011 0 0 Get merch Get the Cossoff mug. Buy Now — $32.95 See more merch