bio-vandalism Share definition Flag Willful defacement or destruction of public or private property using feces, blood, vomit or urine. In an act of bio-vandalism, the disgruntled man smeared feces over the shop owner's window after he was barred from the store. bio-vandalism by Foxylibrarian August 9, 2006 0 0 Get merch Get the bio-vandalism mug. Buy Now — $32.95 See more merch