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Definitions by the fufu editor

let em at em 

informative
: to give, attack, or put forth
reprimand, reprimanding
other ways of saying "let em at em" are; "Let them have it" or " Let them have them"
The boy said "I'll back you up dude". To which one could say "Let em at em".
let em at em by the fufu editor April 19, 2022