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Top Definition
A combination of both a mouth and anus in one.

A sea anemone eats and defecates with its manus.

Manus may also refer to the mouth of someone who only talks shit.
Peter - "My anemone looks better today, hss opened up, you can see his manus now."
Joni - "Haha his white rimmed manus"

Peter - "Your mate should just keep his manus closed."
by such definition July 16, 2014

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