1 definition by gaylord fokker

Top Definition
When something so uberly and 1337tly funny is said, it causes someone to laugh so hard that they get lymphoma. Cancer of the lymph nodes due to lmfaoma, basically.
As we all know, lmfao means "laughing my f***ing ass off", along with the "ma", it has the potential to be a meme.
"Damn, when that fat kid fell on the ice skating rink because he dropped his nachos, I think me and my friends got lmfaoma!
by gaylord fokker February 25, 2007

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