1: The perpetual state of bein' straight fucked up. Constantly engaging in, or provoking, socially and morally unacceptable situations. 2: The after effects of ones mental state subsequent to years of copious drug use and alcoholism.
Pip: "Say Charles, wouldn't you agree that the elderly homeless chap in the courtyard exudes quite an agglomeration of fuckedupness?"
Charles: "Yes, quite, a rather whopping agglomeration of fuckedupness indeed."
Shateefa: "I'm tellin' you guwrl, you aint gonna balee dis. Tanisha slept wit her mama new man, AND bof her sistas husbands too!"
Laquisha: "Damn guwrl! Dats some fuckedupness!"