1 definition by Smat McSplandt

A woman capable of going after numerous guys (single and taken) while completely disregarding their emotions or reactions to her actions.
Alice told you she's fucking some other guy even though you're taking her to prom?! What a she-wolf.

Dude, Ian's she-wolf is here, and she's totally caking on drummer Joe.
by Smat McSplandt April 20, 2009
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