Definitions by Joe Blaze

On One 

To be fucked up on whatever your drug of choice is. It is beyond just tipsy or lightheaded, it's full on faded/twisted/tweaked/trippin/high/etc.

Damn, Rick James was on one back in the 80's.

That bum jackin off in the corner must be on one, damn tweak.

On One by Joe Blaze January 25, 2008