1 definition by Idekman
It's a Japan thing. Apparently, it's from anime. Senpai means someone you're suppose to look up to. (in this case a senior or a teacher if you're thinking of that chick from Misao who liked her teacher.) All in all 'Notice Me Senpai' means you want someone older than you to like you.
by Idekman January 25, 2014