1 definition by DaInfamousKB

pop off

<verb> slang term meaning 'to pop pills,' usually ecstasy.

Before we hit up the club, you tryna pop off?

First I'mma pop off, then I'mma smoke this L.

Why do his eyes look like that?
Oh he popped off earlier.
Oh he's rollin.

by DaInfamousKB August 28, 2007