1) v.t. Neuroadapted.

One is "zapped" when he is depressed on account of being elated at an earlier time.


There is an idea in neurochemistry that the proliferation of pleasure causing neurotransmitters (i.e. dopamine) will actually decrease one's sensitivity to those neurotransmitters (because organisms tend to maintain homeostasis. There various physiological mechanisms. The presence of dopamine, for instance, probably downregulates the dopamine receptor in the post-synaptic neuron, upregulates the enzymes that break down dopamine in the synapse, and upregulates the mechanisms that re-uptake dopamine in the pre-synaptic neuron.

Supposedly, individuals suffering from bipolar disorder tend to overshoot resting levels of neurotransmitters, altrenating between manic and depressed phases.
I got zapped! I was very exited after watching my football team win, and now I am depressed for no reason.

I can't stand strip clubs. I find it too arousing, and I always get zapped the morning after.

Never imbibe alcohol if you are depressed, or you will get zapped.
by Brandon Beaber November 19, 2004
Top Definition
tired, exhausted, worn-out, weary, bushed, drained
Man I'm zapped from the game
by Harry Houdini October 25, 2007
1. exhausted

2. alcohol or drug intoxicated

3. killed(usually said of a character in a video game)
Damn, he just got zapped.
by Light Joker April 01, 2005
to be in a situation of great misfortune
Gabe: "I got AIDS man..."
Jake: "...you have been ZAPPED!"
by PJake January 04, 2004
to be tricked or fooled or told something that dissapoints you
your boss just informed you of having to work late knowing that you had plans. Dude, " you've been zapped"!
by JB & Donny September 27, 2007
When a being is under the influence of a drug called Dextromethorphan (Dextromethorphan HBr), which is found in cough suppressents such as RoboTussin and is also a rising street drug.
She is zapped out of her mind!
by Christopher T. Sawyer II January 24, 2005
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