Terrible body odour. As the late Dimebag Darrell of Pantera put it, zackleys is "when your asshole and your body smell exactly like dog shit"
"You ain't doing nothing 'til you smell like you got zackleys."

"I worked out at the gym the other day and wound up with a bad case of zackleys"
by Donno Aus. Div. November 17, 2005
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When somebody lets out about 22 liters of silent gas from a very filthy, unwashed, shit encrusted asshole and it smells Zackley like SHIT.
As Scooby Doo and the gang had another mystery on their hands, they were cruising in The Mystery machine and all of a sudden Fred smells something coming from the way, way back and he says... "I don't know if it's you Shaggy, or you Scooby, but one of you has a serious case of The Zackleys" Scooby: "Uhhh?" Shaggy: "Zoinks , like, I don't know what The Zackleys are Fred." Fred: "Since Velma is a girl and Daphne is a girl and girls don't fart, and I can see Scooby's asshole, by the process of elimination, the person with The Case of the Zackleys is YOU SHAGGY. You farted and it smells Zackley like shit. Besides, you are such a filthy looking, grimy mother fucker, I'm sure you have a crusty asshole and you must have a load of brown foam in your under britches because I can see it running out your pant leg. Now I know why you always wear brown pants. MYSTERY SOLVED. You Shaggy, have a case of the Zackleys, you filthy mother fucker."
by Doyle_Hargraves February 26, 2020
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bowl full of assholesmorning breath--having bad breath that smells exactly like one's ass.
"man what did you eat? You got the zackleys--your breath smells zackley like your asshole.
by igormanicus April 15, 2006
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Pungent feet stench, that can drive away normal humans on a range of 15 meters, and allure carcass-eating beasts like vultures and hyeenas.

Firstly acknowledged in Pantera's video "Three - Watch it Go!", by Dimebag Darrel, Phd.
John Doe: "Whatta hell is that stench?"
Jane Doe: "It's your mother. She has zackley's disease. Die."
by Metalmassacro June 20, 2008
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