Top Definition
ysf
Abbreviation for 'You Sick Fuck'.
I can't believe you dipped your balls in the pizza dough, ysf.
by Duane April 24, 2005
3 more definitions
YSF
You Stupid F***.
Michael, YSF, you miss the whole point.
by Rudy1957 January 28, 2009
Your So Fucking Sexy
Damn girl YSFS
by SmexxySnarf June 29, 2011
YSF
short for "You're So Funny"
lol that was a good joke! YSF!
by MAN (My anonymous name) February 19, 2011

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