The "O" is obviously a vagina and the "X" is the tape you use to shut that bitches mouth closed.
She totally wants you to stick it in her "0" while you tape an x over her mouth. The amount of sets of "xo" relates to the amount of time a minute she wants you
Natalie: I can't wait to see you tonight babe! xoxoxo
Reed: Should I bring the tape or should you?
Natalie: Oh Reed(Black Jesus)
Hugs And Kisses
xoxo gossip girl
after an email, sms or some type of text; end it with xoxoxo name.