To assiduously ruin your health by any kind of addictive behaviour.
A: You want a smoke?
B: No, I quit two hours ago. But you go ahead and work away, you pot head.
A: Let's fuck off and go for a drink.
B: Sorry dude, I can't. I have to finalize that asap.
A: Don't give me that shit, it's only a job. I've seen you working away for month now. Man, that's sad - you don't have a life anymore.