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Used to ask an indiviudal how things are going. Can be responded to in urban settings by using the word Chillin or in Jamaica by saying Cool
A- Yo man what's up?

B- Chilllin
by ICO777 August 12, 2009
A shortened version of "What's up", which replaces greetings such as "Hello", "How are you?", "What's going on?", etc. This phrase was possibly made popular in the 1940's from a cartoon called Bugs Bunny, when the rabbit said his famous catch phrase, "Eh...What's up, doc?".

If you are not a social recluse then you will most likely be asked "Whatsup?" multiple times a day and be expected to answer with the vague "nothin", "not shit", "chillin", etc.

Other ways to say whatsup:

How's it hanging?, How ya derrin?, How ya doin?, What ho, What it be?, What it do?, What it is?, What's clickin?, What's crackin'?, What's poppin?, What's new?, What gives?, What's cookin?, What's crackalackin?, What's happenin?, etc.
Ex 1:

Ex 2:
Whatsup mothafucka?

Ex 3:
Bob- Hey girl, whatsup?
Lucy- The sky!
Bob- (Smart ass...)

Ex 4:
Bob- Hey man, whatsup?
Jones- Not shit man.
by singingbeauty June 25, 2011
term used when you did something badass
after slapping a bitch thats "whats up"

klucthing it
by benjijuice18 July 26, 2009
What is happEnig friend
what is going on friend?
by Kevin December 04, 2003
A simple greeting. Another way to say hello.
Two people are walking down the street.
Person A: Whats up.
Person B: Whats up.
by crakajack007 March 30, 2009
Something you say to someone who looks sad or troubled
Hey whats up, u don't look like your happy self
by 20104u January 14, 2010
WHAT'S UP! is just a greeting not a question not asking anything just an aknowledgement/ greeting in passing and the only reply in that tone , you have to listen for the tone, is what's! up and keep it moving. Important listen for the tone.
walking down the street and see someone, eyes meet you both have things to do or nothing to do whatever the case you say, what's up! and you keep it moving. don't just say this in any situation you have to use your senses if you don't have any senses don't try it because if you aint feeling it or you convey it in the wrong way it could be misinscrewed in the wrong way that same what's up? could be a challange or a question in which case if you can't reach for your feelings or senses just say hi, that nuetralizes anything other then the greeting.
by "COODIE" DOG April 18, 2010