wadafxup Share definition Flag An apostrophe-less contraction (or word amalgam) meaning "What the fuck is up?" Started by truth.com's PSA campaign. "Hey, did you hear that Jill is dating Johnny now?" "Yeah, wadafxup with that?" wadafxup by Mr.Melon October 5, 2008 0 0 Get merch Get the wadafxup mug. Buy Now — $32.95 See more merch