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To shoot or (sometimes stab)a person several times, usually in an attempt to murder them. Called "wet up" because there is enough blood to soak their clothes, leaving them "wet".
example of wet up:

" Set me up, wet me up, niggas stuck me up
Heard the guns bust but you tricks never shut me up" -2Pac
wet up by MeAgain October 15, 2006
Related Words
to be extremely smart, figuring the worlds most unanswerable (slightly offensive) questions while being extremely sexy at the same time.
damn, gabe and simone are so Wetume
wetume by killerfaggot April 25, 2020
When you're so bored that you typed the prime numbers in the keyboard. True boringness.
Person 1: i am bored lemme search wetuadjlv noone will find this word >:D

Me: nope, there is a definition.
wetuadjlv by Drren123454321 March 29, 2021

Wetussin 

A new brand of cough medicine similar to Robitussin DM that was placed into the market by American rapper Lil' Wayne, a.k.a. Weezy, hence the combination of Robitussin and Weezy (Wetussin). This OTC cough preparation can be purchased at any drug store by the handle and bears the image of Weezy holding a trident posing as Neptune, Greek god of the sea.
Fan: Yo Weezy, I tripped on that shit too and thought I was Neptune!!!!

Weezy: Hey, this guy recognized my lyrics, give him a free handle of Wetussin!!!!
Wetussin by Robotrippin84 January 9, 2009
The liquid state of flatulance, midway between solid and gaseous states.
Dude, that napalm hot curry has given me a bad case of wetulance”
Wetulance by Muzzlenz August 20, 2018

beoup weoup 

A greeting that retards use to signify that they are mentally challenged and extremely horny. This is especially common within the population of them that use hardcore drugs (like black tar heroin)
man 1 (chromes disease) : “BEOUP WEOUP!”
man 2 (normal) : “oh no ! somebody get that retard some puh!!”