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An exclamation of surprise, wonder, excitement, pleasure, etc. Originates from the tv show Home Movies and was used frequently by the character Jason in the episode Definite Possible Murder.
See Home Movies
Jason: Yeah it's a little stuffy in here. Wee-ow!

Brendon: Who moves furniture at 3 o'clock in the morning? Wee-ow!
wee-ow by mikeiscooler June 8, 2009
The typical effeminate (i.e homosexual) way of saying piss off, mainly used by closeted hostile flaming teenagers. Very uncommon among people of the straight persuasion.
John: Hey Billy, let's go tease your brother for being a fairy.

Billy: Hell yeah! Cause that would make us totally masculine.

John: Hey Tulio, get your gay ass back in the kitchen and bake us some cookies, the edible kind fag!

Rafael: Wee off you meanies!
wee off by anon1978 July 1, 2009

Wee Oh Wee 

A sacred race of people that rule the world from the sidelines and want world peace. Their arch-enemies are the sacred Oh Wee Ohs are are determined to undermine and destroy the Wee Oh Wees, which would bring until evil unto the world!
The Great Wee Oh Wee is he leader of the Wee Oh Wees.
a younger child, that has not quite completely developed but has mature-like characteristics
Taylor likes the wee ones.
wee one by jake boehm February 19, 2009
exclamation. a softer way of saying "piss off"
- "hey, you!"
- "wee off!"
wee off by anon55 August 28, 2006

wee hours of the morning

The time immediately after midnight.

The hours of the morning that morning wood is at its peak.
During the wee hours of the morning, throwing up, and covered in dirt, Impala recognized she no longer wanted to be in Zeta Phi Gamma.

Mom, I can't wait for the wee hours of the morning!!