Top Definition
An enema performed using venom (usually from snakes) instead of water. Can be used as an expression that signifies getting extremely and painfully screwed.
-"Bob's into some scary shit, last night he tried to give himself a venema"
"Jesus, he's lucky to be alive!"
-"So not only was the bitch cheating on me with my brother but she maxed out my credit card before they split"
"Dude, what a venema!"
by The venemator July 31, 2006
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