Top Definition
Abbreviation for "Up For".
Often used when enquiring about the possiblity of sexual relations with a member of the opposite sex.
Dude: "Hey baby, upfa?"
Chick: "No"
Dude: "Bitch!"
#upfa #up for it? #upfah #upfa? #enquiring for a root
by Bettsy September 20, 2006
(Pronounced oopfa) Stands for Upper Pussy Fat Area. Or the fat that hangs over a woman's vagina.
Dude, look at Mrs. Walkers UPFA!
#upfa #upper #pussy #fat #area #pooch #fatass
by DustinJ March 13, 2010
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