Top Definition
Ufsi, pronounced 'Oof-see' or 'you-eff-ess-eye' stands for 'Unfit for social interaction', meaning:

'lacking the necessary motivation, competence, meaning, tools, worldview, desire, etc., to function within a social situation at an acceptable level.'

Created and made into a meme by Tao Lin in November, 2011.
b1iber: i think i'm 82% ufsi.

bieber19: whatre u doin tonight, wanna meet up?
me: no, i'm ufsi
bieber19: sweet

wutang89: i feel ufsi
me: whatre u gonna do
wutang89: i don't know
me: sweet
by muumuulover November 26, 2011
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