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refers to a past state of being very drunk and high, from the word twisted. sort of all over the place.
hillary and i took about 15 shots and ten bong hits before we went out last night. we were fuckin twosted.
twosted by marcy December 19, 2004
Related Words

twoasted 

Being drunk and high off weed at the same time.
Man, I went to the club last night and I was twoasted!
twoasted by lala sd gurl September 3, 2010

Twosster 

A guy that keeps girls nudes without them knowing about it
Damn, mike is being a twosster to Jessica
Twosster by Applejack69420 July 21, 2020

twoasted 

adj. - a drunken buzz that usually onsets quickly.
..twoasted of the hizzy fo' shizzy my nizzy...
twoasted by Andy Mack September 25, 2005

Tworsted 

When an individual(s) consume an abnormally large quantity of caffeine and are left with copious amounts of energy
Did you hear about Kerry? She was tworsted after her 9th cup of coffee yesterday, she was just bouncing off the walls!
Tworsted by GemNYC February 22, 2021