Top Definition
Acronym uttered as an exclamation to express extreme satisfaction, joy or excitement.

Stands for: "That's What I'm Fucking Talking About!"
"You just scored front-row tickets to the Navy football - TWIFTA!"

"You just scored with Will's sister - TWIFTA!"
by TwiftaDotCom April 22, 2008
Really lame.
"Andrew is so twifta, all he does is act like a dweeb."
by AndrewIsLame September 10, 2011

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